Abo And Rh Antigens :: titiansjei.space
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18/12/2019 · ABO blood group system, the classification of human blood based on the inherited properties of red blood cells erythrocytes as determined by the presence or absence of the antigens A and B, which are carried on the surface of the red cells. The ABO blood group system is the first described of the human blood groups. AB0 antigensare carbohydrate antigens present on red cell membranes, as: ü glycoproteins ü glucosetransporters ü glycosphingolipids Anti-A, anti-B and anti-A,B antibodies are present only in the blood sera of individuals not possessing that specificity. ABO is the most important of all the blood group systems. There are four different ABO blood groups, determined by whether an individual's red cells carry the A antigen, the B antigen, both A and B antigens, or neither antigens. Table below indicates the preferred ABO and Rh blood types that are used for transfusions. Blood types listed in this table are classified by combining the ABO and Rh groups; for example, type A— means the blood contains A antigens and no Rh antigens, type A means the blood contains both A and Rh antigens. The Seraclone ABO and Rh Grouping Reagents are monoclonal reagents intended for the determination of ABO and Rh antigens on human red blood cells. Seraclone Anti-A and Anti-A,B are capable of reacting with A1, A2, A3 and Ax subgroups. Seraclone Anti-B and Anti-A,B are capable of reacting with B and B weak subgroups.

Following ABO comparison, science discovered other proteins in the blood that are more group-specific than the ABO antigens themselves. Known as Rh, Kell and Duffy blood groups, these proteins give scientists the ability to exclude potential fathers at a slightly higher accuracy rate of about 40%. ABO incompatible plasma in a platelet product can cause significant hemolysis. At the same time, platelets which are ABO incompatible with the patient's plasma can cause smaller platelet count increments. In addition, though platelets do not bear Rh antigens, residual red cells contaminating a platelet unit can express Rh antigens.

These are all referring to different antigens on the surface of red blood cells. Antigens are substances usually on the surface of cells that lead to the production of antibodies, proteins produced by B-cells to identify and eliminate foreign sub. More than 50 antigens have been identified on erythrocyte membranes, but the most significant in terms of their potential harm to patients are classified in two groups: the ABO blood group and the Rh blood group. The ABO Blood Group. Although the ABO blood group name consists of three letters, ABO blood typing designates the presence or absence. In that case, he could be at risk for a condition known as ABO blood type incompatibility, a type of illness known as a hemolytic disease of the newborn HDN.   Another example of an HDN occurs when a mother's blood is Rh-negative and her baby is Rh-positive. Paternity testing Since the inheritance of the ABO Blood Group System is very specific, this serves as one of the first methods to determine the likelihood that the accused father is the father or not. Discovery of the ABO system: In 1900 Karl Landsteiner reported a series of tests, which identified the ABO Blood Group System.

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